Astragalus
Astragalus (Astragalus membranaceus) from NSP is a monocomponent supplement with 420 mg of root extract in each capsule. Supports the immune system, helps adapt to stress, promotes energy and longevity. Article 22751, 100 capsules of 520 mg.
Dietary supplement. Not a medicinal product. Consult a doctor before use. Results may vary.
Description
Astragalus NSP (SKU 22751): Adaptogen with Proven Immunomodulatory and Telomerase Effects
Astragalus membranaceus (黄芪, Huang Qi) is one of the most studied adaptogens in Traditional Chinese Medicine, used for over 2,000 years. Astragalus NSP (SKU 22751) contains standardized root extract with guaranteed levels of polysaccharides and astragalosides.
Mechanism of Action
Immunomodulation via Toll-like Receptors
Astragalus polysaccharides (APS) activate TLR4 receptors on immune cells, increasing NK cell activity by 30–50% and stimulating interleukin-2 and interferon-γ synthesis. APS modulate rather than force immune response, reducing autoimmune risk.
Telomerase Activation: Cycloastragenol
Astragaloside IV and its metabolite cycloastragenol are the only known natural compounds that activate telomerase (TERT enzyme) in human T-lymphocytes, restoring telomere length.
Adaptogenic Effect: HPA Axis Regulation
Astragalus normalizes the hypothalamic-pituitary-adrenal (HPA) axis, reducing peak cortisol under stress without sedation.
Key Clinical Studies
- Harley CB et al. (2011) — Cycloastragenol activates telomerase, lengthens telomeres in T-cells. Rejuvenation Research (PMID: 21250680)
- Liu et al. (2008) — APS enhance T-lymphocyte proliferation (PMID: 18755886)
- Cho WC & Leung KN (2007) — Astragalus enhances antiviral immunity via NK cells (PMID: 17726594)
Composition (per capsule)
- Astragalus membranaceus root extract — standardized for APS and astragalosides
- Gluten-free, lactose-free; GMP-certified NSP facility (USA)
Applications
🛡️ Immunity: Adaptive support during seasonal illness, chronic stress, recovery.
❤️ Cardiovascular: Astragalosides reduce oxidative stress in myocardium.
🔄 Anti-aging: Telomerase activation supports cellular longevity.
⚡ Stress Adaptation: HPA axis normalization, improved physical resilience.
Nutrient Synergy
- Echinacea NSP — enhances antiviral defense
- Vitamin C NSP — improves polysaccharide bioavailability
- Zinc NSP — synergistic T-cell maturation support
💬 Consultant’s Comment
Astragalus is one of the most thoroughly researched adaptogens in modern phytotherapy. In 25 years as an independent NSP partner, I recommend it especially in two situations: when immunity is depleted after prolonged stress or frequent colds, and when someone wants to consciously approach slowing cellular aging.
The key uniqueness of Astragalus is its action on telomerase. Telomeres shorten with each cell division; astragaloside IV slows this process. This is not marketing — these are peer-reviewed studies indexed in PubMed (PMID: 19262543, 20888551).
Practical observation: after 6–8 weeks of regular use, my clients report getting sick less often, recovering faster from physical exertion, and tolerating seasonal changes better. I combine it with Echinacea during peak cold-and-flu season and with Colostrum during exhaustion recovery.
— Oleksii Ihnatenko, independent NSP partner, ID 220701. 25+ years of experience.
Composition
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Ingredients – 1 capsule of 520 mg
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Astragalus Root (Astragalus Membranaceus)
420 mg
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OTHER INGREDIENTS: gelatin, water.
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Gluten and lactose free.
Usage
Take 2 capsules three times a day with meals.
Store in a dry, cool, protected from light place.
What is Astragalus and why has it been used for millennia?
Astragalus membranaceus is a perennial legume that has been a cornerstone of Traditional Chinese Medicine for over 2,000 years. Its primary active compounds — astragalosides (especially astragaloside IV), polysaccharides, and flavonoids — support the immune system, increase the body's resistance to stress, and help maintain adaptive reserves.
How does Astragalus affect the immune system?
Astragalus activates natural killer (NK) cells, T-lymphocytes, and macrophages — the first line of immune defense. Its polysaccharides stimulate interferon and interleukin-2 production, enhancing antiviral protection. Research shows that regular supplementation reduces the frequency and severity of seasonal respiratory infections.
What are telomeres and how is Astragalus related to longevity?
Telomeres are protective caps on the ends of chromosomes that shorten with each cell division. When they become critically short, the cell ages. Astragaloside IV activates the enzyme telomerase, slowing telomere shortening. This is why Astragalus is studied in anti-aging strategies and cellular longevity research (see PubMed PMID: 19262543).
Can Astragalus be taken during stress and fatigue?
Yes, Astragalus belongs to the class of adaptogens — substances that increase non-specific resistance to physical, psycho-emotional, and chemical stress. It helps normalize cortisol levels, supports the adrenal glands, and restores energy balance without the stimulating effect associated with caffeine.
How should Astragalus NSP be taken?
The standard dosage is 1–2 capsules twice daily with meals. For seasonal immune support, a 6–8 week course is sufficient. For adaptogenic support under chronic stress, longer courses of 3–6 months are practiced. Take a 2–4 week break between courses to maintain sensitivity.
Which NSP products combine best with Astragalus?
For comprehensive immune support, Astragalus pairs with NSP Echinacea (antiviral effect) and NSP Vitamin C (antioxidant protection). Under chronic stress and exhaustion, combining with NSP Colostrum — a source of immunoglobulins and growth factors — is highly effective. For cardiovascular support, combine with NSP Coenzyme Q10.
What are the contraindications and precautions for Astragalus?
Astragalus is not recommended for autoimmune conditions (rheumatoid arthritis, lupus, multiple sclerosis) without medical consultation, as it enhances immune activity. Use with caution when taking immunosuppressants. Pregnant and breastfeeding women should consult a healthcare provider before use.
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